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Experience the 'Entourage Effect': The Secret to Better CBD Results

Written by: AtoZ Botanicals Staff



Time to read 7 min

Ever heard of the 'entourage effect'?

While it definitely could make a cool title for a tv show or even a band name, it's a term that has been gaining more attention in the world of CBD.

But what exactly is the CBD entourage effect?

The CBD (cannabidiol) entourage effect refers to the theory that the various components of the cannabis plant work together synergistically to enhance its overall effects. This includes not only CBD, but also other cannabinoids, terpenes, and flavonoids found in the plant. In simpler terms, it's the idea that the whole is greater than the sum of its parts when it comes to cannabis and its effects on the body. In this blog post, we'll explore the entourage effect- how it works, the science behind it, and how it can improve your CBD experience. Read on!

What is the Entourage Effect?

The Entourage Effect, also known as the Ensemble or Synergistic Effect, is a term coined by researchers in 1998.

Basically, it refers to the idea that all the different parts of the cannabis plant create a more powerful therapeutic effect together than they do alone.

This means that when you consume CBD, you're not just getting the benefits of CBD alone. Instead, you're also benefiting from the other compounds present in the plant: the other cannabinoids, terpenes, and flavonoids. These play their own roles in the entourage effect, but what do they do and how does it all work?

Girl taking a CBD Tincture

How does the Entourage Effect Work Exactly?

The science behind the entourage effect is still being studied, but here's what we know so far:

CBD and other cannabinoids found in cannabis interact with our body's endocannabinoid system (ECS). The ECS is responsible for regulating various functions such as mood, pain, sleep, and appetite.

When CBD is consumed, it interacts with the receptors in our ECS, producing various effects. However, when consumed alongside other cannabinoids and compounds found in the cannabis plant, a more complex interaction occurs. This is where the entourage effect comes into play.

Think of the cannabinoids, terpenes, and flavonoids like a close-knit group of friends.

Just as friends can encourage, support, and enhance each other's qualities, these compounds also work in synergy to create a more potent and beneficial effect than they would individually.

Charismatic Cannabinoids

Cannabinoids, like CBD, CBN, and CBG, are the outgoing, charismatic ones. They're the life of the party, interacting directly with the body's endocannabinoid system and influencing receptors like CB1 and CB2, which play crucial roles in regulating mood, pain sensation, appetite, and memory.

Sweet Terpenes

Terpenes, on the other hand, are the aromatic compounds found in cannabis. They're the friends who arrive at the party, bringing an array of fragrances from sweet and fruity to earthy and piney. But they're not just there for their scents.

They also interact with other bodily systems and can enhance the absorption of cannabinoids, thereby amplifying their effects. Terpenes can also influence mood and provide anti-inflammatory benefits.

“Take care of your body, it’s the only place you have to live.”

- Jim Rohn

Friendly Flavonoids

Flavonoids are the quiet ones at the party, but don't let their shy demeanor fool you. They contribute to the cannabis plant's coloration, filter out UV rays, deter pests, and have potential antioxidant, anti-inflammatory, and anti-cancer properties.

Additionally, flavonoids can have a collaborative effect with other compounds in cannabis, enhancing their potential health benefits. Like terpenes, flavonoids can also influence mood and provide anti-inflammatory benefits.

Research on flavonoids is ongoing, but early studies have shown promise in treating conditions such as inflammation, pain, and cancer.

So while they may not be the life of the party like cannabinoids and terpenes, flavonoids play a vital role in the overall benefits of cannabis.

Entourage Effect = The Power of Friendship

When these compounds come together in your body, they don't just co-exist; they influence the receptors and neurotransmitters within our central nervous system more powerfully than they would alone.

Just like a group of friends, where each individual contributes to the overall dynamic, cannabinoids, terpenes, and flavonoids work together, complementing each other's strengths and making up for each other's weaknesses, ultimately creating a harmonious and balanced effect.

CBD Products

What Does the Entourage Effect Feel Like?

The Entourage Effect is what we call the cooperativeness of the compounds, and does not specifically denote a physical sensation.

The amplified effect produced by the cannabinoids, flavonoids, and terpenes working together can lead to a physical effect that you feel.

Some people might feel more relaxed, warm, and notice better relief from discomfort. However, these feelings can differ greatly from person to person and some variables to consider are:

  • Formulation- Our unique formulas are created with different ratios of the compounds in order to achieve specific outcomes

    • . i.e.) Our Stress-Relief Drops /products/calming-drops-cbd-cbn-1700mg are formulated with terpenes that promote relaxation and a calming sensation.
      the Pain Relief Drops /products/cbd-cbg-ultra-pain-relief-drops are designed to increase the body's levels anandamide, a compound that's associated with regulating pain.

      So the balance of compounds within each differs, but each provides the entourage effect by having all the compounds included, just in different amounts.

  • Dosage- Of course, the amount a person takes factors into the physical feeling. Higher doses can lead to more pronounced effects and a lower dosage conversely.

  • Body Chemistry- Because everyone's body chemistry and composition is unique, slight variations in how each individual experiences the entourage effect are to be expected. Keep this in mind when trying a new product or formulation!

  • Quality- The quality of the CBD product can also impact its effects.
    A to Z Botanicals offers the finest selection of broad-spectrum CBD products on the market. Our exclusive extraction methods, the organically and sustainably sourced hemp, and rigorous lab testing all play into what sets AtoZ Botanicals apart in the CBD space.

So, what the entourage effect 'feels like' really depends on a number of factors.
It's also important to note that the effects of the Entourage Effect can be subtle and might just feel like an overall improvement in well-being rather than a distinct, separate feeling.

But Is the Entourage Effect Real? The Scientific Debate

At A to Z botanicals, we answer that with a resounding YES. But, as with much of the world of holistic wellness, CBD's entourage effect has faced criticism.

What They Say

Critics, often from pharmaceutical industries, question the role of terpenes, suggest complexity in discerning specific compound interactions, and argue the theory is being used as a marketing tool.

What We Say

The role of terpenes may not be fully understood yet, but this doesn't negate their potential contribution to the entourage effect.

The complexity of interactions among cannabis compounds is a challenge, but it also indicates a vast area for exploration and discovery. As for the marketing tool argument, while it is true some suppliers may exploit the theory, this doesn't invalidate the potential scientific basis of the entourage effect.

Most importantly, there's a growing body of evidence supporting the entourage effect that hasn't been fully acknowledged or studied. Many studies have shown the potential clinical benefits of CBD-rich Cannabis extracts over purified CBD in treatment-resistant epilepsy and other conditions.

We're proud to share that numerous doctors are now offering our CBD as an alternative to traditional medication. They have been reporting great success, with their patients experiencing significant improvements in their conditions

As more people and doctors learn about the entourage effect, its benefits are becoming widely recognized.

Doctor examining patient

“Wellness is a connection of paths: knowledge and action.”

- Joshua Holtz

What are the Benefits of the Entourage effect?

When the different compounds work together for the entourage effect, the benefits include

  1. Better Effectiveness: The compounds work better together than alone.

  2. Fewer Side Effects : Some compounds can help lessen the side effects of others.

  3. Specific Health Benefits: Different combinations can provide different health benefits.

  4. Better Absorption: Some compounds can help your body absorb others better.

  5. No Tolerance Build-up: The entourage effect might stop users from building a tolerance to these substances.

Broad-Spectrum CBD: The Entourage Effect without the High

Broad-spectrum CBD is good for people who want the added benefits of the Entourage Effect but don't want the high that comes with THC. It has many parts of the cannabis plant, but not THC.

Full-spectrum CBD, on the other hand, has all parts of the cannabis plant, including THC. So it can give you the full benefits of the Entourage Effect, but it might also make you feel a 'high' because of the THC.

CBD isolate is just pure CBD. It doesn't have the other parts of the cannabis plant, so it doesn't give the extra benefits of the Entourage Effect.

In short, broad-spectrum CBD is a great middle option. It gives you the extra benefits of the Entourage Effect without the high from THC. It's a good choice for those who want to avoid getting high but still want the other benefits from the cannabis plant.

Final Thoughts

In short, using the whole cannabis plant can be incredibly beneficial. Different parts work together to boost benefits, reduce side effects, and stop you from building a tolerance, which could make you feel healthier overall.

Broad-spectrum CBD is a good choice if you want these benefits without the high from THC. It's a practical way to bring balance to your life.

Imagine feeling more balanced and less stressed, thanks to the natural compounds in the cannabis plant working together in your body. By using broad-spectrum CBD, you can get closer to this reality. You can enjoy all the benefits of the cannabis plant, but without the high.

Are you ready to try it out for yourself? Start exploring CBD with confidence, and see the difference it can make when different parts of the plant work together. Try it today for a more natural approach to health and wellness, and see the potential of the entourage effect in your life.

If you want to learn more about CBD, you can check out more on our store

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